Molecular Genetics
Biology 495
Fall 2004, 11:15 - 12:05 AM, MWF Room 101 TCNW
Instructor: Dr. Claire A. Rinehart
Office: 121 TCNW Phones: 745-5997, 843-9028 (H)
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Introduction, Genes are DNA
Genes are DNA
The Interrupted gene
Content of the genome
Content of the genome
Clusters and repeats
HOLIDAY
Messenger RNA
Protein Synthesis
Protein Synthesis
Using the Genetic Code
Protein Localization
Protein Localization
Transcription
Transcription
The operon
Regulatory circuits
Phage strategies
The replicon
The replicon
FALL BREAK
DNA Replication
DNA Replication
Recombination and repair
Recombination and repair
Transposons
Retroviruses and Retrotransposons
Rearrangement of DNA
Chromosomes
Nucleosomes
Promoters and enhancers
Activating transcription
Controlling chromatin structure
Controlling chromatin structure
RNA splicing and processing
Catalytic RNA
Immune Diversity
Immune Diversity
Protein Trafficking
Signal Transduction
THANKSGIVING BREAK
THANKSGIVING BREAK
Signal Transduction
Cell Cycle and Growth Regulation
Cell Cycle and Growth Regulation
Oncogenes and Cancer
Oncogenes and Cancer
Gradients, cascades and signaling pathways
FINAL EXAM 10:30 - 12:30
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Required Text:
Genes VIII by Benjamin Lewin, 2004.
Grading and Student Responsibilities:
- Undergraduates:
Up to 31 quizzes or projects worth 10 points each.
Class participation 30 points.
Final exam worth 150 points.
- Graduates:
Same as undergraduates plus a 6-8 page paper reviewing primary journal articles
on a molecular genetics topic of interest and approved by the instructor.
The paper will be worth 100 points. The paper should be carefully referenced
and written in your own words. Any plagarism will result
in a grade of 0 points and possible discipline by the department. The term
paper is due in the instructor's mailbox (room 200 TCNW) by 4 PM on Dec. 1st!
- FINAL EXAM will be held on Friday, Dec. 17 at 10:30 AM-12:30 PM,
and will be comprehensive.
Students will be responsible for reading the assignments in the text BEFORE
they attend class. Students are responsible to study the lecture/discussion
material and to complete all assignments and quizzes. Grades will be assigned
as shown below based on the percentage of total points earned from the final
exam, projects, quizzes and term papers.
Grades
A = 90 to 100%
B = 80 to 89.99%
C = 70 though 79.99%
D = 60 through 69.99%
F = Below 60%
Academic Integrity: It is expected that each student will do his/her own work
at all times. Therefore cheating/academic dishonesty in any form (plagiarism,
altering exams, crib sheets etc.) will result in a failing grade for the course,
and possible university discipline.
"Students with disabilities who require accommodations (academic adjustments
and/or auxiliary aids or services) for this course must contact the Office for
Student Disability Services, Room 445, Potter Hall. The OFSDS telephone number
is (270) 745-5004 V/TDD. Please DO NOT request accommodations directly from
the professor or instructor without a letter of accommodation from the Office
for Student Disability Services."