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IntroductionIn Bio121, for your pleasure and edification, we have developed several computer simulations/previews of the laboratory exercises. To view these exercises you will need the (free) Flash plug-in. If you do not see anything in the space below, you can download it here. You may have to close and restart your browser to complete the installation, its easy - just follow the instructions.
A Pipet can have two types of markings on it: TC ot TD. TC means "to contain". A pipet with this marking has been calibrated to contain a specified volume of liquid. A pipet marked TD (the more common type of pipet) has been calibrated "to deliver" a specified volume of liquid. When filling a pipet, the tapered end is held beneath the surface of the liquid at all times. The liquid is drawn into the pipet by suction until the level is equal to or greater than the volume of liquid to be delivered. Pipettes are designed to be used with a hand pump or bulb, of which there are many varieties. Never use your mouth with a pipet! We typically have 1, 5, 10, and 25 ml pipettes available for use in the lab. The pipettes are clearly labelled as to the volume markings and subdivisions. It is imperative that you read the label on the pipette body before using it to know precisely how to read it. Click the image for a larger view (new window). Examine the necks of the pipets for their markings. The arrows indicate the starting and finishing points for delivering 10 mL from each pipet. When loading the pipette, the volume is read at the bottom of the meniscus that forms on top of the column of liquid Volumetric pipets are designed to transfer a fixed amount of liquid when filled to the mark (e.g. 10 mL and only 10 mL). There is generally only one "fill-line" on a volumetric pipet. Other pipets are graduated, so they can deliver any volume of liquid up to the capacity of the pipet. Mohr pipets are graduated but the graduations stop at a baseline before the pipet begins to narrow (see arrow on left). To accurately transfer fluid with this type of pipet, the meniscus must be precisely on a calibration mark both at the beginning and at the end of a transfer. Serological pipets are the type we will use most often in Bio 121. Serological pipets have no base mark (the graduations continue onto the tip) and are graduated to deliver. that means you let all the (measured) liquid in the pipet exit.
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