DNA replication is semiconservative (Fig.
12.1).
DNA replication begins at specific chromosomal sites called origins
(Fig. 12.5).
Prokaryotes have a single origin.
Eukaryotes have many origins.
Initiation of DNA replication begins as proteins recognize and bind
origins forming an open complex.
E. coli origin recognition (Fig.
12.7). = Prokaryote example.
SV40 origin recognition (Fig.
12.12). = Eukaryote example.
Growing replication fork (Fig.
12.9a).
Bond formation (movie).
Leading and Lagging Strand Formation (movie).
E. coli (movie).
Components of replication
complex (Fig 12.11).
Lagging-strand synthesis
(Fig. 12.9b).
Ligase reaction (Fig.
12.9c).
SV40 (Fig.
12.12). = Eukaryote example.
Replicating the ends of linear DNA (Fig.
12.13) (movie).
Properties of DNA Polymerases (Table
12.1).