Fig. 10.9 Localization of RNA polymerase
and regulator footprints on lac operon.
Fig.
10.11 (a) alignment of multiple promoters shows conservation at some
positions upstream of transcriptional start site. (b) shows the consensus
sequences for an E. coli promoter. (c) shows how mutations at the
lac promoter can result in increased or decreased transcription according
to how well the mutation matches the consensus promoter sequence.
Fig. 10.30 Consensus promoter sequence
for a eukaryotic gene illustrating the % conservation at promoter vs the
adjacent area.
Table 10.1 Various sigma factor recognition
sites.
Fig. 10.12 Operator sites often have inverted
repeat structures.
Fig. 10.14 Binding of dimeric form of regulator
is usually via alpha helices inserted into the major groove of DNA.
Fig. 10.17 Positive regulation of the Lac
operon via cAMP and CAP.
Fig. 10.19 How enhancers can work.
Fig. 10.21 Many gene responses depend on
two proteins, one for sensing and one for responding.
