Introduction to Molecular and Cell Biology, Biol. 220
Lecture 9: Translation in eukaryotes
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Introduction to Molecular and Cell Biology, Biol. 220 Lecture 9: Translation in eukaryotes |
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Translation
Initiation of protein synthesis in eukaryotes (Fig. 4.37).
What is the protein sequence coded for by the eukaryotic mRNA below?
AUG AAU ACA UGG AGG AGG UAC GUC CUU AUG GUG CAU UGA UAA UAG
Interaction between poly(A) and intiation complexes are important for initiation
and stability of mRNA (Fig. 4.41a).
Internal ribosome entry at IRES sites (Fig. 4.38).
Protein synthesis on endoplasmic reticulum (ER) (Movie)
Fig. Movie of Protein Synthesis on the ER and Subsequent Protein Transport.
If you put an ER signal onto an mRNA that is normally found in the cytoplasm, where will the protein end up in the cell?
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