Biology 220

Fall 2004, 9:30 - 10:45, TR Room 224 TCNW,

Prerequisites: Biology 120 and Chemistry 120

Instructor: Dr. Claire Rinehart, Office: 121 TCNW, Phone: 745-5997, 843-9028 (h)

Office Hours: T, W, F 12:20-1:10

 Date
Topic
Text Chapter
Aug. 24 1-Overview. How to eat an elephant.  L1  
Aug. 26 2-Covalent and non-covalent bonds   L2
2.1, 2.2
 Aug. 31 3-Amino acids and proteins L3
2.2, 3.1
 Sept. 2 4-Functional design of proteins L4
3.2
Sept. 7 5-Enzymes L5
3.3, 3.5
Sept. 9 6-Structure of nucleic acids L6
4.1, 4.2
Sept .9-14 Online Practice Exam 1 available  
 Sept 14 In-class Exam 1  
Sept. 16  7-The three roles of RNA in protein synthesis L7
4.4
Sept. 21 8-Formation of proteins in prokaryotes L8
4.5
Sept.  21 9-Formation of proteins in eukaryotes L9
4.5
 Sept. 23  10-Biomembranes L10
5.1 5.2
Sept. 28 11-Organelles of the eukaryotic cell L11
5.3
 Sept. 30 12-Chromosomal DNA organization L12
10.4 & 5
    Review Sheet
 Oct. 1-13 Exam 2  
 Oct. 5 13-DNA replication machinery L13
4.6
Oct.  12 14-Topoisomerases
4.6
 Oct.12 15-DNA damage and repair L15
23.5
Oct. 14 16-Recombination in homologous DNA L16
9.5
Oct. 19 17-Genes L17
 10.1, 2, 9.1
Oct. 21 18-Transcription initiation in prokaryotes L18
Oct. 26 19-Transcription initiaion in eukaryotes L19
11.1 - 6
     
Nov. 4 Exam 3
Nov. 9 20-Transcriptional regulation L20
11.1 - 6
Nov. 11 21-Transcription termination L21
 11.7
Nov. 11 22-Processing of RNA L22
 12.1, 12.2, 12.5
Nov. 16 23-Nuclear transport L23
12.3
Nov. 16 24-Post-transl organelle protein transport L24
16.5 - 16.6
Nov. 18 25-Pathway of secretory proteins
16.1 -16.3
Nov.18 26-Vesicle sorting and trafficing L26
171, 17.4
Nov23. 27-Actin cytoskeleton L27
 19.1
Nov23. 28-Dynamics of actin assembly L28  19.2 - 19.4
Nov 25 Thanksgiving Vacation
 Nov. 30 Exam 4 over lectures 20 - 26 only
*** Final Exam Study Guides  
 Dec. 2 29-Microtubule structures L29
20.1
 Dec. 2 30-Microtubule dynamics L30
20.2-20.3
 Dec. 2 31-Intermediate filaments L31
19.5
   
Dec.7 32-Cell-to-cell signaling L32
13
Dec.7 33-Cell-cell adhesion and communication L33
6.1 - 6.6
 Dec 9 37-Cancer Cell Cycle L37
7.1
 TBA 34-Plasmids
7.1
 TBA 35-Bacteriophage
7.2
 TBA 36-Mobile DNA
9.3
 Dec10-15 Exam 5  
 Dec10-15 FINAL EXAM  

 

Text:

Molecular Cell Biology by Lodish, Berk, Zipursky, Matsudaira, Baltimore and Darnell, Fifth Edition

Exams:

There will be four in-class exams worth 100 points each. Practice exam will be made available electronically via CourseInfo for a week prior to the in-class exam.

The FINAL EXAM will be held on Thursday, December 11 from 10:30 - 12:30, and will be a comprehensive in-class exam worth 200 points. In this exam students will not be able to use or refer to source material other than what is on their exam. No exam scores will be dropped in the calculation of the final grade.

 

Daily Lectures and Study Aids

I encourage students to review the web site before the lecture and try the study quizzes before coming to class. The book provides more details than the web site and some very good examples of the topic. Use the text as a study resource for more details and examples. I will give a few points to encourage you to study the material before attending class. The study quizzes will be administered electronically via CourseInfo and you can use these to determine your mastery of the topics. I will award 2 points for each quiz successfully completed, before the lecture, with a score higher than 70%. You will be able to take the study quizzes as many times as you like. I will award the points 1 hour before the lecture so all quizzes must be completed by then.

At the beginning of each lecture period I will briefly review the lecture topics for the day and answer questions that you may have from your studies.

Most days I will try to bring some problems or projects that you can work on in small groups if there is time at the end of the lecture period. These will generally be worth 1-2 points each.

 

Grading and Student Responsibilities:

Students will be responsible for reading assignments online and in the text as well as the lecture/discussion material.

Students will be responsible to attend exams during the scheduled periods. Exceptions MUST be discussed with the instructor PRIOR to the scheduled exam.

Grades will be assigned as shown below based on the percentage of total points earned from the final exam, projects, and quizzes.

Grades

A = 90 to 100%

B = 80 to 89.99%

C = 70 though 79.99%

D = 60 through 69.99%

F = Below 60%

Academic Integrity: It is expected that each student will do his/her own work at ALL times. Therefore cheating/academic dishonesty in any form (plagiarism, altering exams, crib sheets etc.) will result in a failing grade in the course and other university disciplinary actions .


"Students with disabilities who require accommodations (academic adjustments and/or auxiliary aids or services) for this
course must contact the Office for Student Disability Services, Room 445, Potter Hall. The OFSDS telephone number is
(270) 745-5004 V/TDD. Please DO NOT request accommodations directly from the professor or instructor without a
letter of accommodation from the Office for Student Disability Services."