Introduction to Molecular and Cell Biology
Biol. 220-001,
Syllabus Fall 1999

INSTRUCTOR:

Dr. Claire A. Rinehart
TCNW 213
Phones: 745-6006 (w) or 843-9028 (h)
TEXTBOOK:
The Cell: A Molecular Approach
Author: Geoffrey M. Cooper
Publisher: ASM Press and Sinauer Associates, Inc
Copyright: 1997
ISBN 0-87893-119-8
OTHER SUPPORT:
HyperCell CD
Author: Gene Williams
Publisher: Garland Publishing
1000A Sherman Avenue, Hamden, CT 06514-1337
TO ORDER: 1-800-627-6273
www.garlandpub.com
COURSE DESCRIPTION:
Introduction to the molecular and cell biology of both prokaryotic and eukaryotic cells. The objective of this course is to achieve an understanding of the molecular mechanisms underlying biological complexity. You will learn about the various components of the cell and how those components are encoded and controlled by the molecular blueprint of life.
PREFERRED PREREQUISITES:
Biology 120, 121; Chemistry 122, 123
ATTENDANCE:
Students are expected to be punctual and present at every meeting. Make-up exams/quizes will only be given under exceptional circumstances.
GRADES:
During classes a quiz/project assignment will be given over the material covered for that day worth 10 points each. Also, three one-hour exams worth 100 points each will be given as indicated in the course schedule. An additional comprehensive final exam will be given during finals week and will be worth a total of 150 points.  Grades will be assigned as shown below
A= 90-100%
B= 80-89.99%
C= 70-79.99%
D= 60-69.99%
F= below 60%
LECTURE / CHAPTER
SUBJECT 
DATE 
1- Chapter 1 (4-8) 
2- Chapter 1 (9-18) 
3- Chapter 2 
4- Chapter 2 
5- Chapter 2 
6- Chapter 2 (54-62) 
7- Chapter 2 (45-7,76-7) 
8- Chapter 3 (92-93) 
9- Chapter 2 (76-77) 
10- Chapter 2 (77-81)		 Overview of Cells 
Overview of Cells 
Carbohydrates & Lipids 
Amino Acids & Peptide Bonds 
Protein Structure 
Enzymes 
Structure of DNA 
Structure of DNA/RNA 
Structure of RNA 
Cell Membranes		 August 23 
August 25 
August 27 
August 30 
September 1 
September 8 
September 10 
September 13 
September 15 
September 20
  EXAM 1 over lectures 1-9 September 22
11- Chapter 12 
12- Chapter 9-11 
13- Chapter 9-11 
14- Chapter 8 
15- Chapter 8 (326-341)		 Cell Surface 
Eukaryotic Cell Structure 
Eukaryotic Cell Structure 
The Nucleus 
Structure of Chromosomes 		 September 24 
September 27 
September 29 
October 4 
October 6
  FALL BREAK October 7-8
16- Chapter 3 
17- Chapter 5 
18- Chapter 3		 DNA Replication 
DNA Replication 
DNA:The Genetic Material 		 October 11 
October 13 
October 15
  LASTDROP WITH W October 18
  Exam 2 over lectures 10-17 October 18
19- Chapter 5 (199-220) 
20- Chapter 5 (190-198) 
21- Chapter 6 (225-229) 
22- " 
23- Chapter 6 (235-240) 
24- Chapter 7 (273-298) 
25- " 
26- Chapter 9 
27- Chapter 13 		 Genetic Recombination / Rearrangement 
DNA Repair 
Transcription/Prokaryotes 
Transcription/Eukaryotes 
Transcription/Eukaryotes 
Translation/Prokaryotes 
Translation/Eukaryotes 
Intracellular Protein Sorting &Transport 
Cell Signaling 		 October 20 
October 25 
October 27 
October 29 
November 1 
November 3 
November 8 
November 10 
November 12
  EXAM 3 over lectures 19-26 November 15
28- Chapter 6 (229-234) 
29- "		 Control of Gene Expression, Prokaryotes 
Control of Gene Expresssion, Prokaryotes		 November 17 
November 22
  THANKSGIVING November 24-26
30- Chapter 3 (108-109) 
31- Chapter 1 (33-34) 
32- Chapter 5 (211-219) 
33- Chapter 6 (240-267) 
34- Chapter 6 (240-267)		 Plasmids 
Bacteriophages 
Transposons 
Gene Expression in Eukaryotes 
Gene Expression in Eukaryotes		 November 29 
December 1 
December 3 
December 6 
December 8
  FINAL EXAM, comprehensive 
(Finals Week) 		 December 13 
10:30am-12:30