Introduction to Recombinant Genetics- Biology 350

Laboratory Index Page
Lecture Index
Date
Topics
Book Chapter
Sept. 1
Introduction -information resources, stats  
3
Genetic Organization  
8
What is Recombinant Gene Technology 1, 2
10
Restriction enzymes and Ligases 4
15
Restriction enzyme maps 4
17
DNA Isolation -purpose, types of clones, source of material 3
22
Phage isolation 3
24
Enzyme tools needed for cloning 4, + Handout
29
Cloning vectors for E.coli & other bacteria 6
25
Cloning vectors for Eukaryotes 7
Oct. 1
Introduction of DNA into cells 5
6

Hybridization techniques
Strategies for selecting the right clone

8
13
DNA sequencing , primer synthesis 10
15
Sequence assembly 12
20
Determining coding potential of a sequence 12
22
Determining the function of an unknown gene 12
27
Studying transcription, Northerns, microarrays, RT-PCR 11
29
Proteome Analysis& 2 hybrid system 12
Nov. 3
Metabolomics
Making antibodies against proteins and their use
 
5
Mutagenesis  
   
10
Knockouts and siRNA inhibition of gene expression 15
12
Protein expression ...continued. 13
17
Isolation of purified recombinant proteins
Determining protein structure, MALDI
13
19

Basics in Forensics 

16
24
...continued  
Dec. 1
Phylogenetics and Species identification 16
3
Gene Therapy 14
8
Project  
10
Project  
Dec. 17
Final Exam 10:30 - 12:30 AM  

 

 

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